Structural formula of guaiol · C₁₅H₂₆O.
Guaiol
Woody, rose, spicy
Guaiol is a sesquiterpene alcohol found in many medical cannabis strains. Aroma: woody, rose, spicy. In Tier-A literature it is most strongly associated with inflammation. terpen.cloud lists every currently available pharmacy strain high in guaiol.
Effect profile
Guaiol in the cannabis context
Guaiol is a sesquiterpene alcohol from guaiac wood and a specialist with an oncological, anti-inflammatory side profile. Its inflammation score of 1.5 rests on a documented effect via the PPAR-γ signaling pathway, a mechanism that also plays a role in metabolic and tumor contexts. Guaiol is found in guaiac trees and a few myrrh species.
Anxiety relief, sleep, mood, focus, activation, pain and appetite are not part of the profile. Oncological research on guaiol has gained momentum in recent years and makes it an interesting longtail terpene.
In cannabis, guaiol is found in strains like Liberty Haze and Chocolope, rarely dominant. You recognize it by the woody, rosy, slightly smoky aroma, similar to guaiac wood. Higher guaiol levels signal an effect profile centered on inflammation and cellular signaling pathways.
Pharmacological notes: Antibacterial effect in the metabolite context, oncological signaling pathways with active research.